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Catalog Number | orb66895 |
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Category | Antibodies |
Description | Rabbit polyclonal to EZH2.Enhancer of zeste homolog 2 (EZH2) belongs to the Polycomb-group (PcG) family. Members from this family form multimeric protein complexes, which play a role in maintaining the transcriptional repressive state of genes over successive cell generations. EZH2 interacts with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. The complex it forms with EED/PRC2 promotes the methylation of Lys-9 and Lys-27 of histone H3, which in turn leads to the transcriptional repression of the target genes. |
Clonality | Polyclonal |
Species/Host | Rabbit |
Conjugation | Unconjugated |
Reactivity | Human |
Buffer/Preservatives | 0.01% NaN3 |
Purity | Affinity purification |
Immunogen | middle region of human EZH2 |
UniProt ID | Q15910 |
MW | 85 |
Tested applications | WB |
Dilution range | WB:1:1000-1:5000 |
Storage | -20°C |
Alternative names | anti-EZH2 antibody,anti-ENX1 antibody,anti-ENX1 an Read more... |
Note | For research use only |
Western blot analysis of total cell extracts from human Hela using EZH2 antibody