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| Catalog Number | orb2703643 |
|---|---|
| Category | Antibodies |
| Description | Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular diseases. |
| Target | Evolocumab Biosimilar (Anti-PCSK9 Reference Antibody) |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| MW | 2308.59784531593 |
| Antibody Type | Biosimilar Antibody |
| CAS Number | 1256937-27-5 |
| Formula | C129H135F5N24O12 |
| SMILES | FC1C=CC(=CC=1)C(C)N1C(C(=CC2C=CC(=C(C=2)OC)N2C=NC(C)=C2)N/C/1=N\CC1CC1)=O.FC1C=CC(=CC=1)C(C)N1C(C(=CC2C=CC(=C(C=2)OC)N2C=NC(C)=C2)N/C/1=N\CCCC)=O.FC1C=CC(=CC=1)C(C)N1C(C(=CC2C=CC(=C(C=2)OC)N2C=NC(C)=C2)N/C/1=N\CCCO)=O.FC1C=CC(=CC=1)C(C)N1C(C(=CC2C=CC(=C(C=2)OC)N2C=NC(C)=C2)N/C/1=N\CC)=O.FC1C=CC(=CC=1)C(C)N1C(=NC(=CC2C=CC(=C(C=2)OC)N2C=NC(C)=C2)C1=O)OC |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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