Evolocumab Antibody

SKU: orb1297795

Description

Evolocumab is a human monoclonal antibody that inhibits PCSK9, preventing its interaction with the LDL receptor. It is widely used in preclinical and clinical research for studying hypercholesterolemia and atherosclerotic cardiovascular disease, including in vitro binding assays and in vivo models of lipid metabolism.

Research Area

Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• Target: NF-κB,TLR,Serine Protease,Others,LDLR
• Molecular Weight: 144 kDa
• Purity: 98.30% (May vary between batches)
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Concentration: 140 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AMG 145, AMG145, AMG-145, atherosclerotic cardiovascular disease, Evolocumab, hypercholesterolemia, Inhibitor, LDLR, PCSK9, inhibit, Serine endopeptidases, Ser/Thr Protease, Serine proteases, Threonine proteases, Repatha

Quick Database Links

Gene Symbol

NF-κB,TLR,Serine Protease,Others,LDLR