(±)-Evodiamine

SKU: orb1982007

Description

(±)-Evodiamine is a natural topoisomerase I inhibitor that suppresses adipogenesis and inflammation via modulation of IGF-1/HIF-1α, IL-6/STAT, and NF-κB pathways. It has been studied in vitro and in vivo for its roles in inhibiting cancer cell invasion, promoting apoptosis, and blocking TNF-induced Akt activation.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 518-18-3
• MW: 303.36
• Formula: C₁₉H₁₇N₃O
• SMILES: CN1C2C3=C(C=4C(N3)=CC=CC4)CCN2C(=O)C=5C1=CC=CC5
• Target: Others
• Solubility: DMSO:8 mg/mL (26.37 mM);10% DMSO+90% Corn Oil:0.5 mg/mL (1.65 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

151289