Ethyl cinnamate

SKU: orb1297381

Description

Ethyl cinnamate

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 103-36-6
• MW: 176.21
• Purity: 99.53%
• Formula: C₁₁H₁₂O₂
• SMILES: C(=CC(OCC)=O)C1=CC=CC=C1
• Target: Parasite,NO Synthase,VEGFR,ROS,Apoptosis,Calcium Channel
• Solubility: DMSO:50 mg/mL (283.75 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.35 mM)

Bioactivity

• Target IC50:
  Tonic contractions (chenylephrine-induced):0.38 mM|Tonic contractions (high K+-induced):0.30 mM
• In Vitro:
  Parameters, including biomass, F(v)/F(m) (maximal photochemical efficiency of PSII), Ф(PSII) (actual photochemical efficiency of PSII in the light), FDA, and PI staining fluorescence, were measured the results showe the following: (1 the Inhibition on biomass increased a the exposure concentration increased. 1 mg/L Ethyl cinnamate was sufficient to reduc the total biomass of C. vulgaris the 48 h and 72 h EC50 Values were 2.07 mg/L (1.94-2.20) and 1.89 mg/L (1.82-1.97). (2) After 24 h of exposure to 2-4 mg/L Ethyl cinnamate the photosynthesis of C. vulgaris almost ceased, manifesting in DФ(PSII) being close to zero. After 72 h of exposure to 4 mg/L Ethyl cinnamate the Fv /Fm of C. vulgaris dropped to zero. (3) Ethyl cinnamate also affecte the cellular physiology of C. vulgaris, but these effects resulted in the Inhibition of cell yfield rather than cell deat

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

clearing, CalciumChannel, Calcium Channel, NOSynthase, Inhibitor, inhibit, NO Synthase, Ethyl cinnamate, fragrance, ROS, reagent

Compound Identifiers

PubChem CID

7649