(E)-Ethyl cinnamate

SKU: orb1989728

Description

(E)-Ethyl cinnamate is a natural flavor compound isolated from Spondias mombin. It is used in fragrance and flavor research and serves as a reference standard in biochemical studies for investigating its reported anti-inflammatory and antimicrobial properties in vitro.

Key Properties

• CAS Number: 4192-77-2
• MW: 176.21
• Purity: 99.64%
• Formula: C₁₁H₁₂O₂
• SMILES: C(=C/C(OCC)=O)\C1=CC=CC=C1
• Target: Others

Bioactivity

• In Vivo:
  (E)-Ethyl cinnamate (1 mg/kg/d, 3 mg/kg/d, 60 mg/kg/d) inhibited tumor growth and angiogenesis in HT29 nude mouse colonic cancer xenograft model, and hepatotoxicity and nephrotoxicity were not detected.
• In Vitro:
  (E)-Ethyl cinnamate inhibited high K and deoxyadrenaline (PE) -induced tetanic contraction in a concentration dependent manner with IC50 Values of 0.30 mM and 0.38 mM, respectively (E)-Ethyl cinnamate (0-80 μM) significantly inhibite the colony-forming ability of colon cancer cells HT29 and SW480 in a concentration dependent manner.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

Compound TBBP04531

Compound Identifiers

PubChem CID

637758