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Ethacrynic acid

SKU: orb1302754

Description

Ethacrynic acid is a potent loop diuretic that acts by inhibiting the Na+/K+/2Cl- cotransporter (NKCC2). Its additional inhibition of glutathione S-transferase and Wnt signaling underpins its research use in oncology, particularly for studying cytotoxicity in leukemia and tumor cell models in vitro.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number58-54-8
MW303.1
Purity>98%
FormulaC13H12Cl2O4
SMILESCCC(=C)C(=O)C1=CC=C(OCC(O)=O)C(Cl)=C1Cl
TargetGlutathione
SolubilitySoluble in DMSO

Storage & Handling

StorageRT
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Etacrynic acid

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Key Properties

No computed properties available.

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200 mg
$ 150.00
1 g
$ 230.00
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