EA-B2L

SKU: orb2802488

Description

EA-B2L is a potent degrader of glutathione S-transferase P1 (GSTP1) with a DC50 of 48 µM, composed of Ethacrynic acid conjugated to Boc2Lys. This PROTAC molecule is a valuable chemical tool for investigating GSTP1's role in oncology, supporting both in vitro and in vivo cancer research studies.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1354444-72-6
• MW: 729.73
• Formula: C₃₅H₅₄Cl₂N₄O₈
• SMILES: C(C(CC)=C)(=O)C1=C(Cl)C(Cl)=C(OCC(NCCCCCCNC([C@@H](NC(OC(C)(C)C)=O)CCCCNC(OC(C)(C)C)=O)=O)=O)C=C1
• Target: E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176419304