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ERK-IN-3

SKU: orb1218498

Description

ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2055597-12-9
MW473.93
Purity>98% (HPLC)
FormulaC22H25ClFN7O2
SMILESO=C(C1=CN(C2=NC(NC3CCOCC3)=NC=C2C)C=N1)N[C@@H](C4=CC(F)=CC(Cl)=C4)CN
TargetERK
SolubilityDMSO:250 mg/mL (527.50 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ASN007 free base

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  • ERK-IN-3 [orb1298335]

    99.55% (May vary between batches)

    2055597-12-9

    473.93

    C22H25ClFN7O2

    5 mg, 10 mg, 25 mg, 50 mg, 1 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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500 mg
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2 mg
$ 140.00
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