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Catalog Number | orb1980728 |
---|---|
Category | Antibodies |
Description | Envafolimab (ASC 22) is a humanized monoclonal antibody targeting programmed cell death ligand-1 (PD-L1), with antitumor activity. It blocks the interaction between PD-L1 and PD-1, and is used in studies of solid tumors. |
Clonality | Monoclonal |
CAS Number | 2102192-68-5 |
Antibody Type | Recombinant Antibody |
Concentration | 13.93 mg/mL |
Purity | 95.00% |
Conjugation | Unconjugated |
Target | Envafolimab |
Biological Activity | Envafolimab (ASC 22; KN 035), a recombinant humanized single-domain anti-PD-L1 antibody, integrates the anti-PD-L1 domain with the Fc fragment of the human IgG1 antibody. It inhibits the PD-L1 and PD-1 interaction with an IC 50 of 5.25 nM, indicating its research potential for solid tumors [1] [2] [3]. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA, FC | |
Human, Monkey | |
Monoclonal | |
Unconjugated |