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Endothelin Receptor Antibody

SKU: orb3032073

Description

Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetEndothelin Receptor
Molecular Weight145.28 kDa
Purity95.90% (May vary between batches)
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration5.49 mg/mL
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Patecibart, GMA301, GMA-301

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

1 mg
$ 240.00
5 mg
$ 530.00
10 mg
$ 740.00
25 mg
$ 1,120.00
50 mg
$ 1,530.00
100 mg
$ 2,000.00
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days
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