Endothelin Receptor Antibody

SKU: orb3032073

Description

Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2642374-04-5
MW	145.28 kDa
Purity	95.00%
Target	Endothelin Receptor

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Patecibart, GMA301, GMA-301

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Gene Symbol

Endothelin Receptor

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