Encelimab Antibody

SKU: orb1942295

Description

Encelimab, an anti-LAG3 monoclonal antibody, blocks LAG-3 binding to MHC class II, promoting T-cell activation and anti-tumor immunity. It demonstrates preclinical efficacy by reducing tumor burden in lymphoma models like A20 xenografts, both as monotherapy and with anti-PD-1, supporting cancer immunotherapy research.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2173096-82-5
• MW: 144.57 kDa
• Purity: 95.00%
• Target: LAG-3

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

LAG-3