EN523

SKU: orb1297827

Description

EN523 is a selective small molecule inhibitor that covalently targets the allosteric, non-catalytic cysteine residue C23 of OTUB1, a K48-linkage specific deubiquitinase. This compound is a valuable chemical probe for studying OTUB1's role in DNA damage response and immune signaling pathways in both cellular and biochemical assays.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2094893-05-5
• MW: 234.25
• Purity: 99.36% (May vary between batches)
• Formula: C₁₂H₁₄N₂O₃
• SMILES: Cc1ccc(o1)N1CCN(CC1=O)C(=O)C=C
• Target: Others,DUB
• Solubility: DMSO:25 mg/mL (106.72 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

allosteric cysteine C23, deubiquitinase, OTUB1 recruiter, inhibit, non-catalytic, Inhibitor, EN 523, EN523, EN-523

Compound Identifiers

PubChem CID

126817009