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LEB-03-144

SKU: orb1983074

Description

LEB-03-144 is a deubiquitinase-targeting chimera (DUBTAC) designed to stabilize the WEE1 kinase by recruiting OTUB1 to it, utilizing AZD1775 linked to EN523. It has demonstrated WEE1 protein stabilization in cellular models like HEP3B hepatoma cells, providing a tool for investigating targeted protein stabilization in cancer research.

Images & Validation

Key Properties

MW817.94
FormulaC43H51N11O6
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information