EMT inhibitor-3

SKU: orb2944965

Description

EMT inhibitor-3 (compound 11i) is a small molecule that potently inhibits proliferation, migration, and invasion in SK-N-SH neuroblastoma cells (IC50 = 2.5 µM). It triggers intrinsic apoptosis via the mitochondrial pathway, modulating Bax/Bcl-2, cytochrome c release, and caspase-9/3 activation, making it a useful tool for studying cancer biology and EMT in vitro.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 2930726-89-7
• MW: 592.45
• Formula: C₂₉H₂₁F₂N₃O₄Se
• SMILES: N#C[Se]CCCOC=1C=CC=2C=C(C(=O)OC2C1)C(=O)N3N=C(C=4C=CC(F)=CC4)CC3C5=CC=C(F)C=C5
• Target: Apoptosis,Cytochromes P450,Caspase,Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455451