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TGF-βRI inhibitor 3

SKU: orb2944882

Description

Compound 9ac (TGF-βRI inhibitor 3) is a selective TGF-β pathway inhibitor with IC50 values of 0.63 μM for ALK5 and 13 μM for c-Src kinase. This tool compound is used in vitro to study fibrotic diseases, cancer metastasis, and EMT within TGF-β signaling research.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number666729-57-3
MW351.396
FormulaC21H21NO4
SMILESO=C(C=1C=C(C(=CC1OC=2C=CN=C3C=C(OC)C(OC)=CC32)C)C)C
TargetSrc,TGF-beta/Smad,ALK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information