Empesertib (BAY 1161909)

SKU: orb1220237

Description

BAY 1161909 is a potent Mps1 inhibitor, with an IC50 of < 1 nM. BAY 1161909 also shows anti-tumor effect, suppressing the proliferation of Hela cells, with an IC50 of < 400 nM.(In Vitro):BAY 1161909 is a potent Mps1 inhibitor, with an IC50 of < 1 nM. BAY 1161909 also shows anti-tumor effect, suppressing the proliferation of Hela cells, with an IC50 of < 400 nM.

Key Properties

• CAS Number: 1443763-60-7
• MW: 559.61
• Purity: >98% (HPLC)
• Formula: C??H??FN?O?S
• SMILES: FC1=CC=C([C@@H](C)C(NC2=CC=C(C3=CN4N=C(NC5=CC=C(S(C)(=O)=O)C=C5OC)N=C4C=C3)C=C2)=O)C=C1
• Target: Mps1/TTK
• Solubility: DMSO : ≥ 35 mg/mL (62.54 mM)\n\nH2O : < 0.1 mg/mL (insoluble)

Bioactivity

• In Vitro:
  BAY 1161909 is a potent Mps1 inhibitor, with an IC50 of < 1 nM. BAY 1161909 also shows anti-tumor effect, suppressing the proliferation of Hela cells, with an IC50 of < 400 nM.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BAY 1161909

Quick Database Links

Gene Symbol

Mps1/TTK