Emlenoflast

SKU: orb1298267

Description

Emlenoflast (MCC7840) is a potent and selective small molecule inhibitor targeting the NLRP3 inflammasome. It is a valuable research tool for investigating NLRP3-driven pathologies, such as inflammatory and autoimmune diseases, in both cellular assays and animal models.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1995067-59-8
• MW: 388.48
• Purity: 99.43% (May vary between batches)
• Formula: C₁₉H₂₄N₄O₃S
• SMILES: N(C(NS(=O)(=O)C1=NN(C(C)C)C=C1)=O)C2=C3C(=CC4=C2CCC4)CCC3
• Target: NOD,NOD-like Receptor (NLR)

Bioactivity

• Target IC50:
  NLRP3:< 100 nM

Storage & Handling

• Storage: store at low temperature,keep away from moisture,The compound is unstable in solution. Please use soon | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, inflammatory, inflammasome, NLR, NLRP3, NOD-like Receptor, NODlikeReceptor, NODlikeReceptor(NLR), NODlike Receptor (NLR), NOD-like Receptor (NLR), Inhibitor, MCC7840, MCC-7840, MCC 7840, Emlenoflast, sulfonylurea

Compound Identifiers

PubChem CID

122480653