ELOVL6-IN-2

SKU: orb1298274

Description

ELOVL6-IN-2 is a potent and selective small molecule inhibitor of ELOVL6, suitable for oral administration. It is a valuable research tool for investigating fatty acid metabolism in contexts such as metabolic disorders, non-alcoholic fatty liver disease (NAFLD), and cancer, with utility in both in vitro and in vivo studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1067647-43-1
• MW: 579.49
• Purity: 99.95% (May vary between batches)
• Formula: C₂₈H₂₃F₆N₃O₄
• SMILES: Cc1[nH]n(-c2ccc(OC(F)(F)F)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
• Target: Others
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (5.69 mM);DMSO:135 mg/mL (232.96 mM)

Bioactivity

• Target IC50:
  ELOVL6:34 nM(mouse )
• In Vivo:
  ELOVL6-IN-2 potently and proportionally suppressed the elongation index of fatty acids in the liver in mice.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

plasma, potent, selective, dose-proportionally, liver, inhibit, orally, Inhibitor, ELOVL6, ELOVL6 IN 2, ELOVL6IN2, ELOVL-6-IN-2, ELOVL6-IN-2

Compound Identifiers

PubChem CID

44139567