ELOVL6-IN-2

SKU: orb1219136

Description

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1067647-43-1
• MW: 579.49
• Purity: >98% (HPLC)
• Formula: C₂₈H₂₃F₆N₃O₄
• SMILES: CC(C)(CC(N1c2ccccc2)=C2C(C(F)(F)F)(C(C3=O)=C(C)NN3c(cc3)ccc3OC(F)(F)F)C1=O)CC2=O
• Target: ELOVL6
• Solubility: DMSO:90mg/ml(155.31mM; Need ultrasonic)

Bioactivity

• In Vivo:
  Animal model: Male C57BL/6J mice. Dosage: 0.1~1 mg/kg. Administration: p.o. Result: Potently and dose-proportionally suppressed the elongation index in the liver. Animal model: Male C57BL/6J mice. Dosage: 10 mg/kg. Administration: p.o. Result: Demonstrated highly liver penetrable. Animal model: Male C57BL/6J mice. Dosage: 1 mg/kg. Administration: p.o. Result: Exhibited sustained plasma exposure.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ELOVL6