EHMT2 (M) Antibody, Rabbit Polyclonal

SKU: orb67069

Description

Rabbit polyclonal to EHMT2.Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) belongs to the histone-lysinemethyltransferase family, Suvar3-9 subfamily. EHMT2 specifically mono-and dimethylates 'Lys-9' ofhistone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tagfor epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT2also weakly methylates 'Lys-27' of histone H3 (H3K27me). In addition, EHMT2 is required for DNAmethylation, which is independent of its histone methyltransferase activity. Furthermore, EHMT2methylates non-histone proteins, including p53/TP53, CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6,KLF12 and itself.

Images & Validation

• Tested Applications: WB
• Dilution range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: middle region of human EHMT2
• Molecular Weight: 132
• Purity: Affinity purification

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Disclaimer: For research use only

Alternative Names

anti-EHMT2 antibody,anti-Histonelysine Nmethyltransferase EHMT2 antibody,anti-Euchromatic histonelysine Nmethyltransferase 2 antibody,anti-HLAB associated transcript 8 antibody,anti-Histone H3K9 methyltransferase 3 antibody,anti-H3K9HMTase 3 antibody,anti-Lysine Nmethyltransferase 1C antibody,anti-Protein G9a antibody,anti-BAT8 antibody,anti-C6orf30 antibody,anti-G9A antibody,anti-KMT1C antibody,anti-NG36 antibody

Western blot analysis of total cell extracts from human Hela using EHMT2 antibody

Quick Database Links

UniProt

Q96KQ7