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EFNA5 (C) Antibody, Rabbit Polyclonal

EFNA5 (C) Antibody, Rabbit Polyclonal

Catalog Number: orb131880

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$ 440.00
Catalog Numberorb131880
CategoryAntibodies
DescriptionRabbit polyclonal to EFNA5. Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in co-cultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Species/HostRabbit
ClonalityPolyclonal
Tested applicationsWB
ReactivityHuman
ImmunogenC-terminal region of human EFNA5
Concentration100 μg/ml BSA
Dilution rangeWB:1:1000-1:3000
PurityAffinity purification
ConjugationUnconjugated
MW26
UniProt IDP52803
Storage-20°C
Buffer/Preservatives0.01% NaN3
Alternative namesanti Ephrin-A5 antibody, anti AL-1 antibody, anti
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NoteFor research use only
Application notes< strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
< br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human EFNA5.
Expiration Date12 months from date of receipt.