Ebselen

SKU: orb1310258

Description

Ebselen (CCG-39161) is a synthetic organoselenium compound that functions as a potent glutathione peroxidase mimetic, scavenging reactive oxygen species (ROS) and inhibiting enzymes like nitric oxide synthase and protein kinase C. Its cytoprotective and anti-inflammatory properties support its use in research models of neurodegeneration, ischemia, and inflammation, both in vitro and in vivo.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 60940-34-3
• MW: 274.18
• Purity: 99.78%
• Formula: C₁₃H₉NOSe
• SMILES: O=C1N([Se]C=2C1=CC=CC2)C3=CC=CC=C3
• Target: Calcium Channel,Virus Protease,Phosphatase,COX,HIV Protease
• Solubility: H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.29 mM);DMSO:40 mg/mL (145.89 mM)

Bioactivity

• Target IC50:
  Mpro:0.67 μM (IC50)|COVID-19 virus:4.67 μM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Phosphatase, PZ 51, PZ51, PZ-51, QSOX1, peroxidase, SPI1005, SPI-1005, SPI 1005, VDCC, voltage-dependent, Virus Protease, VirusProtease, mimetic, inhibit, monophosphatase, IMPase, Mpro, glutathione, Human immunodeficiency virus, inositol, Inhibitor, HIV, HIVProtease, HIV Protease, Ebselen, COX, COVID-19, CCG 39161, blood-brain, barrier, Ca channels, C145, Calcium Channel, Ca2+ channels, CalciumChannel, CCG39161, CCG-39161

Compound Identifiers

PubChem CID

3194