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Catalog Number | orb67179 |
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Category | Antibodies |
Description | Rabbit polyclonal to E4F1.Transcription factor E4F1 may function as a transcriptional repressor. It may also function as aubiquitin ligase mediating ubiquitination of chromatin-associated TP53. E4F1 functions in cell survivaland proliferation through the control of the cell cycle. It functions in the p53 and pRB tumorsuppressor pathways and regulates the cyclin CCNA2 transcription. It is identified as a cellular targetof the adenoviral oncoprotein E1A, and it is required for both transcriptional activation and repressionof viral genes. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | C-terminal region of human E4F1 |
Dilution range | WB:1:500-1:2000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 83 |
UniProt ID | Q66K89 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-E4F1 antibody,anti-Transcription factor E4F1 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human 293T using E4F1 antibody