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E3 ligase Ligand 8

SKU: orb1307448

Description

E3 ligase Ligand 8 serves as a recruiter for ubiquitin ligase in the construction of PROTAC molecules. These bifunctional degraders are widely utilized in both in vitro and in vivo cancer research to induce the targeted ubiquitination and subsequent proteasomal degradation of oncogenic proteins.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1225383-33-4
MW530.61
Purity98.86% (May vary between batches)
FormulaC31H34N2O6
SMILESCC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
TargetLigand for E3 Ligase
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.22 mM);DMSO:90 mg/mL (169.62 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, LigandforE3Ligase, Ligand for E3 Ligase, Ligands for E3 Ligase, E3 ligase-recruiting Moiety, E3 ligase Ligand 8, E-3 ligase Ligand 8

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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10 mg
$ 70.00
25 mg
$ 100.00
50 mg
$ 140.00
100 mg
$ 200.00
200 mg
$ 270.00
DispatchUsually dispatched within 5-10 working days
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