Dupilumab Antibody

SKU: orb1707978

Description

Dupilumab (REGN-668) is a fully human monoclonal antibody targeting the IL-4 receptor alpha subunit, thereby blocking IL-4 and IL-13 signaling. It is widely used in research models of atopic dermatitis and other type 2 inflammatory diseases to investigate therapeutic mechanisms in both in vitro and in vivo settings.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Target	IL Receptor,Interleukin
Molecular Weight	149.8 kDa
Purity	98% by SEC-HPLC
Purification	3-step chromatographic process
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Liquid, PBS, pH 6.
Concentration	152.8 mg/mL
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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REGN668, REGN-668, REGN 668, SAR231893, SAR-231893, SAR 231893, Dupilumab, IL Receptor, ILReceptor, IL-4, IL-13

Quality Guarantee

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Gene Symbol

IL Receptor,Interleukin

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