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DPA-714

SKU: orb1308368

Description

DPA-714 is a high-affinity TSPO ligand (Ki=7 nM) that can be radiolabeled with fluorine-18 for PET imaging. Its application, as [18F]DPA-714, enables specific in vivo visualization of neuroinflammation in models of neurological disorders and brain tumors, supporting preclinical research.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number958233-07-3
MW398.47
Purity99.85% (May vary between batches)
FormulaC22H27FN4O2
SMILESCCN(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(OCCF)cc1
TargetOthers,Mitochondrial Metabolism
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.02 mM);DMSO:41.67 mg/mL (104.57 mM)

Bioactivity

Target IC50
TSPO:(ki)7 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DPA 714, DPA714, DPA-714, inhibit, Inhibitor, TSPO

Similar Products

  • DPA-714 [orb1217424]

    >98% (HPLC)

    958233-07-3

    398.47

    C22H27FN4O2

    200 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 g
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 160.00
1 ml x 10 mM (in DMSO)
$ 160.00
10 mg
$ 210.00
25 mg
$ 360.00
50 mg
$ 500.00
100 mg
$ 690.00
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