Docosanedioic acid?

SKU: orb1940149

Description

BEHENIC ACID is a alkyl-chain-based PROTAC linker. BEHENIC ACID is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Key Properties

• CAS Number: 505-56-6
• MW: 370.574
• Purity: >98% (HPLC)
• Formula: C₂₂H₄₂O₄
• SMILES: OC(=O)CCCCCCCCCCCCCCCCCCCCC(O)=O
• Target: GSK-3α|GSK-3β

Bioactivity

• In Vitro:
  ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Behenic Acid

Quick Database Links

Gene Symbol

GSK-3α|GSK-3β