Docosanedioic acid

SKU: orb1297879

Description

Behenic acid is a saturated fatty acid that serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as an alkyl-chain-based spacer in PROTAC design. Its application supports research in targeted cancer therapy, facilitating the development of novel bioconjugates for in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 505-56-6
• MW: 370.567
• Purity: 98.00% (May vary between batches)
• Formula: C₂₂H₄₂O₄
• SMILES: O=C(O)CCCCCCCCCCCCCCCCCCCCC(O)=O
• Target: PROTAC Linker,ADC Linker
• Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Docosanedioic acid, Docosanedioic acid , ADCLinker, ADC Linkers, Alkyl-Chain, ADC Linker, Antibody-drug conjugates linkers, Inhibitor, inhibit, Non-cleavable, PROTACLinker, PROTAC Linkers, PROTAC Linker

Compound Identifiers

PubChem CID

244872