Divarasib

• Catalog Number: orb1737448
• Category: Small Molecules
• Description: Divarasib
• CAS Number: 2417987-45-0
• Purity: 0.9879
• MW: 622.06
• SMILES: C[C@H]1CN(CCN1c1nc(OC[C@@H]2CCCN2C)nc2c(F)c(c(Cl)cc12)-c1nc(N)cc(C)c1C(F)(F)F)C(=O)C=C
• Formula: C₂₉H₃₂ClF₄N₇O₂
• Biological Activity: Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 μM. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibits tumor cell growth. It is being investigated for use in solid tumors, including non-small cell lung and colorectal cancers and other types of cancer.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.