Dinutuximab

SKU: orb1290219

Description

Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions of human IgG1 heavy-chain and kappa light-chain

Images & Validation

• Tested Applications: SDS-PAGE
• Reactivity: Human

Key Properties

• Antibody Type: Biosimilar Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1-kappa
• Target: ganglioside GD2
• Molecular Weight: 145000.0 Da
• Purity: > 95%
• Conjugation: Unconjugated

Storage & Handling

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks). Store at -20 °C 12 months. Store at -80°C long term
• Buffer/Preservatives: PBS buffer pH 7.5
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

14.18, MAb-14.18, MOAB Ch14.18

CAS Number: 1363687-32-4

Quick Database Links

Gene Symbol

ganglioside GD2