Dihydrolipoic acid

SKU: orb1940460

Description

Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.

Key Properties

• CAS Number: 462-20-4
• MW: 208.33
• Purity: >98% (HPLC)
• Formula: C₈H₁₆O₂S₂
• SMILES: OC(=O)CCCCC(S)CCS
• Target: Antioxidant
• Solubility: In Vitro: DMSO : 100 mg/mL (479.98 mM)

Bioactivity

• In Vivo:
  Animal model: Adult male Sprague-Dawley (SD) rats (weight, 200-220 g). Dosage: 15 mg/kg, 30 mg/kg, 60 mg/kg. Administration: Injected intraperitoneally daily. Result: Treatment with 30 mg/kg and 60 mg/kg improved the body weight gain as compared to the LPS group.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

USAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA

Quick Database Links

Gene Symbol

Antioxidant