Dihydrolipoic acid

SKU: orb1306431

Description

Dihydrolipoic acid (USAF XR-12) is a potent dithiol antioxidant effective against diverse reactive oxygen species like peroxynitrite and hydroxyl radicals at 0.01-0.5 mM. It is widely used in research on oxidative stress, neurodegeneration, and metabolic disorders in both cellular and animal models.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 462-20-4
• MW: 208.34
• Purity: ≥98% (May vary between batches)
• Formula: C₈H₁₆O₂S₂
• SMILES: C(C(CCS)S)CCCC(O)=O
• Target: Antioxidant,ROS,Reactive Oxygen Species
• Solubility: DMSO:50 mg/mL (239.99 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (4.8 mM)

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

radical, Reactive Oxygen Species, Reduced lipoic acid, Reduced thioctic acid, oxygen, oxidation-reduction, ROS, USAF XR-12, Inhibitor, HO-1, ERK, inhibit, Lipopolysaccharide, Nrf2, NLRP3, Neuroinflammation, 6,8-Dihydrothioctic acid, Antioxidant, anti-inflammatory, Dihydrolipoic acid, DHLA, Depression, centered

Compound Identifiers

PubChem CID

421