Dictamnine

SKU: orb1220717

Description

Dictamnine shows anticholinesterase anti-inflammatory mutagenic and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix colon and oral carcinoma cells.

Key Properties

• CAS Number: 484-29-7
• MW: 199.21
• Purity: >98% (HPLC)
• Formula: C₁₂H₉NO₂
• SMILES: COc1c2ccoc2nc2ccccc12
• Target: Antifection
• Solubility: DMSO:50 mg/mL (250.99 mM)

Bioactivity

• In Vivo:
  Animal model: HCT116 xenograft tumor model. Dosage: 50 and 100 mg/kg. Administration: p.o. , three times a week. Result: Inhibited tumor growth. Reduced HIF-1α and Slug protein level in the tumor tissue.
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• In Vitro:
  Western blot analysis. Cell line: HCT116 cells. Concentration: 0-100 μM. Incubation time: 12 h. Result: Inhibited HIF-1α (synthesis but not degradation) and Slug protein accumulation under hypoxia.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dectamine

Quick Database Links

Gene Symbol

Antifection