Dexrazoxane

SKU: orb1306016

Description

Dexrazoxane (ICRF-187) is a cardioprotective iron chelator used in research to mitigate anthracycline-induced cardiotoxicity. It also acts as a topoisomerase II inhibitor, arresting cell division in vitro and in vivo, making it a valuable tool in oncology and cardioprotection studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 24584-09-6
• MW: 268.27
• Purity: 99.88% (May vary between batches)
• Formula: C₁₁H₁₆N₄O₄
• SMILES: C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
• Target: Others,Apoptosis,Ferroptosis
• Solubility: Methanol:1.25 mg/mL (4.66 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.46 mM);DMSO:57 mg/mL (212.47 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ICRF 187, ICRF187, ICRF-187, Inhibitor, NSC169780, NSC-169780, inhibit, NSC 169780, ADR 529, ADR529, ADR-529, Dexrazoxane

Compound Identifiers

PubChem CID

71384