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Denosumab Antibody

SKU: orb1297798

Description

Denosumab is a human monoclonal antibody administered via subcutaneous injection. It functions by binding to and inhibiting RANKL, thereby suppressing osteoclast formation and activity. This mechanism is utilized in research models of osteoporosis, bone metastasis, and rheumatoid arthritis to study bone resorption pathways.

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetApoptosis,Caspase,RANKL/RANK,NF-κB
Molecular Weight144.71 kDa
Purity99.90% (May vary between batches)
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration62.5 mg/mL
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Denosumab, Cancer, Inhibitor, inhibit, Immunoglobulin G 2, Immunoglobulin G2, Immunoglobulin G-2, Nuclear factor-κB, Nuclear factor-kappaB, NF-κB, Osteoporosis, Ranmark, RANKL, RANK

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

1 mg
$ 220.00
5 mg
$ 580.00
10 mg
$ 820.00
25 mg
$ 1,230.00
50 mg
$ 1,630.00
100 mg
$ 2,210.00
Free Secondary Antibody (20 ul)0/0

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