Dehydroglyasperin C

SKU: orb1682804

Description

Dehydroglyasperin C is a potent inducer of NQO1 and phase 2 enzymes, exhibiting strong antioxidant and chemopreventive properties. Its neuroprotective action against glutamate-induced oxidative stress in neuronal cells is mediated through the Nrf2-Keap1 and PI3K/AKT pathways, leading to HO-1 upregulation, as demonstrated in vitro.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 199331-35-6
• MW: 354.4
• Formula: C₂₁H₂₂O₅
• SMILES: COc1c(CC=C(C)C)c(O)cc2OCC(=Cc12)c1ccc(O)cc1O
• Target: IκB/IKK,NADPH,Akt,COX,TNF,p38 MAPK,PI3K,ERK,NF-κB,Autophagy,JNK,Nrf2,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

480775