Dehydrocorydalin

SKU: orb1222397

Description

Dehydrocorydaline exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSCLC cells. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). Dehydrocorydaline has anti-inflammatory and antinociceptive effects. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

Key Properties

• CAS Number: 30045-16-0
• MW: 366.43
• Purity: >98% (HPLC)
• Formula: C₂₂H₂₄NO₄+
• SMILES: CC1=C2C=CC(=C(C2=C[N+]3=C1C4=CC(=C(C=C4CC3)OC)OC)OC)OC
• Target: Others
• Solubility: In Vitro: DMSO : 25 mg/mL (68.23 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

13-Methylpalmatine

Quick Database Links

Gene Symbol

Others