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DDX17 (N) Antibody, Rabbit Polyclonal

SKU: orb131832

Description

Rabbit polyclonal to DDX17. Probable ATP-dependent RNA helicase DDX17 belongs to the DEAD box helicase family and the DDX5/DBP2 subfamily. DDX17 is an RNA-dependent ATPase activity. DDX17 is involved in transcriptional regulation and is a transcriptional coactivator for estrogen receptor ESR1. DDX17 increases ESR1 AF-1 domain-mediated transactivation. Additionally, DDX17 synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and is probably involved in skeletal muscle differentiation. Furthermore, DDX17 is required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation.

Research Area

Infectious Disease & Virology

Images & Validation

Tested ApplicationsIP, WB
Dilution RangeWB:1:1000-1:3000
ReactivityHuman, Mouse
Application Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human DDX17.

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenN-terminal region of human DDX17
Molecular Weight80
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.01% NaN3
Concentration100 μg/ml BSA
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti Probable ATP-dependent RNA helicase DDX17 antibody, anti DEAD box protein 17 antibody, anti DEAD box protein p72 antibody, anti RNAdependent helicase p72 antibody

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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol
IP
Immunoprecipitation
View Protocol

Available Sizes

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100 μl
$ 540.00
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Free Secondary Antibody (20 ul)0/0

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