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DBCO-PEG4-Ahx-DM1

DBCO-PEG4-Ahx-DM1

Catalog Number: orb1988485

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Catalog Numberorb1988485
CategorySmall Molecules
DescriptionDBCO-PEG4-Ahx-DM1 is a drug-linker conjugate that combines the microtubulin inhibitor DM1 (mertansine), an antibody-conjugatable maytansinoid designed to reduce systemic toxicity and improve tumor-specific delivery, with the linker DBCO-PEG4-Ahx, for developing antibody drug conjugates (ADCs).
Purity98.00%
MW1297.92
Biological ActivityDBCO-PEG4-Ahx-DM1 is a drug-linker conjugate that combines the microtubulin inhibitor DM1 (mertansine), which is an antibody-conjugatable maytansinoid designed to reduce systemic toxicity and improve tumor-specific delivery, with the linker DBCO-PEG4-Ahx, for the development of antibody drug conjugates (ADCs).
FormulaC68H89ClN6O17
SMILESCOC1=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]2(O)NC(OC([C@@H](C)C(O3)[C@]3(C)[C@@H](OC([C@H](C)N(C)C(CCCCCNC(CCOCCOCCOCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)CC7=O)C2)=O)=CC(N7C)=C1Cl
Storage-20°C
NoteFor research use only
  • DBCO-PEG4-Ahx-DM1 [orb1473152]

    [2479378-44-2]

    1297.92

    C68H89ClN6O17

    10 mg