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Catalog Number | orb1473152 |
---|---|
Category | Small Molecules |
Description | DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin?inhibitor?DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a?microtubulin?inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. |
MW | 1297.92 |
CAS Number | [2479378-44-2] |
Formula | C68H89ClN6O17 |
SMILES | COC1=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]2(O)NC(OC([C@@H](C)C(O3)[C@]3(C)[C@@H](OC([C@H](C)N(C)C(CCCCCNC(CCOCCOCCOCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)CC7=O)C2)=O)=CC(N7C)=C1Cl |
Note | For research use only |