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dAURK-4

SKU: orb1983211

Description

dAURK-4 is a potent and selective Aurora A (AURKA) degrader derived from Alisertib. It demonstrates anticancer activity and is a valuable chemical probe for studying AURKA biology in both cellular and in vivo cancer models.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2705844-81-9
MW1035.47
FormulaC52H52ClFN8O12
SMILESCOc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(=O)NCCCOCCOCCOCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
TargetPROTACs,Aurora Kinase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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dAURK-4 (orb1983211)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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