dAURK-4 hydrochloride

SKU: orb1983210

Description

dAURK-4 hydrochloride is a selective degrader of the Aurora A kinase (AURKA), demonstrating antiproliferative and anticancer activity. It is utilized in cancer research to study targeted protein degradation and has been evaluated in both cellular and animal models of oncology.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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Target	PROTACs,Aurora Kinase
Molecular Weight	1071.93
Purity	99.44%
Formula	C₅₂H₅₃Cl₂FN₈O₁₂
SMILES	O=C(C1=CC=C(NC2=NC(C3=C(C(C4=C(OC)C=CC=C4F)=NC5)C=C(Cl)C=C3)=C5C=N2)C=C1OC)NCCCOCCOCCOCCCNC(COC6=CC=CC(C(N7C8C(NC(CC8)=O)=O)=O)=C6C7=O)=O.Cl

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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dAURK-4 hydrochloride (2705844-81-9 free base), AuroraKinase, Aurora Kinase, Aurora A

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Compound Identifiers

PubChem CID

163196236 ↗

Key Properties

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No computed properties available.

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