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Dalotuzumab Antibody

SKU: orb1980643

Description

Dalotuzumab (MK-0646) is a humanized anti-IGF-1R monoclonal antibody that blocks oncogenic signaling, promoting tumor cell apoptosis and cell cycle arrest. Its research applications include in vitro studies of IGF-1R pathway inhibition and in vivo combination therapy models for various cancers, demonstrating synergistic effects with chemotherapeutic agents.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityRecombinant
TargetIGF-1R,Apoptosis
Molecular Weight146.36 kDa
Purity99.30% (May vary between batches)
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration6.13 mg/mL
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

h7C10, MK-0646

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Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

1 mg
$ 290.00
5 mg
$ 690.00
10 mg
$ 1,030.00
25 mg
$ 1,500.00
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days
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