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CZh226

SKU: orb1986946

Description

CZh226 is a highly selective PAK4 inhibitor with a Ki of 9 nM, showing over 300-fold selectivity against PAK1. It potently suppresses the migration and invasion of A549 lung cancer cells in vitro by modulating PAK4/LIMK1/cofilin signaling pathways, making it a valuable tool for oncology and metastasis research.

Images & Validation

Key Properties

MW411.89
FormulaC20H22ClN7O
SMILESO=C(N1C[C@@H](C)NCC1)C2=NC3=CC=C(Cl)C=C3C(NC4=NNC(C5CC5)=C4)=N2
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • CZh226 [orb2279706]

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Key Properties

No computed properties available.

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CZh226 (orb1986946)

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