λ-Cyhalothrin

SKU: orb1940353

Description

lambda-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group.lambda-Cyhalothrin is used to control a wide range of pests in a variety of applications.lambda-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.(In Vitro):The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes.λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro.λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control.λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles.(In Vivo):The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min.

Key Properties

• CAS Number: 91465-08-6
• MW: 449.85
• Purity: >98% (HPLC)
• Formula: C₂₃H₁₉ClF₃NO₃
• SMILES: CC1(C)[C@H](\C=C(/Cl)C(F)(F)F)[C@@H]1C(=O)O[C@@H](C#N)c1cccc(Oc2ccccc2)c1
• Target: Sodium Channel
• Solubility: In Vitro: DMSO : 33.33 mg/mL (74.09 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Icon | Karate | lambda-Cyhalothrin

Quick Database Links

Gene Symbol

Sodium Channel