Cyclamic acid sodium

SKU: orb1819334

Description

Sodium cyclamate is a widely used artificial sweetener and carbonic anhydrase inhibitor. Research applications include investigating its anticonvulsant properties in electroshock seizure models and its potential roles in cancer-related studies, utilizing both in vitro and in vivo experimental approaches.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 139-05-9
• MW: 201.22
• Purity: 99.84% (May vary between batches)
• Formula: C₆H₁₂NNaO₃S
• SMILES: [Na+].[O-]S(=O)(=O)NC1CCCCC1
• Target: Necroptosis,Carbonic Anhydrase,Apoptosis
• Solubility: DMSO:7.5 mg/mL (37.27 mM);H2O:45 mg/mL (223.64 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.97 mM)

Bioactivity

• In Vivo:
  Cyclamic acid sodium (6000 mg/kg/day; intraperitoneal injection; for 5 days) induced acute DILI mouse model can be established successfully. The toxicity of sodium cyclamate to the liver showed a dose-response and time-response relationship. Cyclamic acid sodium induced liver, heart, and kidney injury are closely related to the inflammatory response mediated by TNF-α and IL-1β.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sodiumcyclamate, Cyclamic acid sodium, Cyclohexylsulfamicacidsodium, Carbonic Anhydrase, Carbonic anhydrase, CarbonicAnhydrase

Compound Identifiers

PubChem CID

23665706