Cyclamic acid

SKU: orb1310149

Description

Cyclamic acid is an artificial sweetener typically used as its sodium or calcium salt (cyclamate). Its use is restricted in some countries due to disputed potential carcinogenicity. This compound is employed in research applications involving taste perception, metabolic studies, and toxicological assessments in both in vitro and in vivo models.

Research Area

Cell Biology

Key Properties

• CAS Number: 100-88-9
• MW: 179.24
• Purity: 99.92% (May vary between batches)
• Formula: C₆H₁₃NO₃S
• SMILES: OS(=O)(=O)NC1CCCCC1
• Target: Necroptosis,Others,Apoptosis
• Solubility: DMSO:55 mg/mL (306.85 mM);Ethanol:34 mg/mL (189.69 mM);H2O:33 mg/mL (184.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.16 mM)

Bioactivity

• In Vitro:
  Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners in food and pharmaceuticals. Cyclamic acid is in use in more than 50 countries, especially in combination with other sweeteners, to eliminate aftertaste. However, the petition on Cyclamic acid, calcium and sodium cyclamate is being held in abeyance with the FDA in the USA (CFSAN - Office of Food Additive Safety, 2006).
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclamate, Cyclamic acid, Cyclohexylsulfamic acid, artificial, Inhibitor, NSC 220327, inhibit, NSC220327, NSC-220327, sweetener

Compound Identifiers

PubChem CID

7533