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Catalog Number | orb1742769 |
---|---|
Category | Antibodies |
Description | CXCR7 antibody recognizes C-X-C chemokine receptor type 7 (CXCR7), now known as atypical chemokine receptor 3 (ACKR3). This chemokine receptor (with a predicted molecular weight of 41 kDa) binds the chemokines CXCL11 and CXCL12 and other non-chemokine ligands such as adrenomedullin and MIF. ACKR3 plays important roles in cardiovascular and neuronal development and acts as a scavenger receptor to regulate both chemokine- and opioid peptide-dependent signaling. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | ELISA, FACS, ICC, IHC-Fr, IHC-P, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | IgG |
Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CXCR7. The exact sequence is proprietary. |
Antibody Type | Primary Antibody |
Concentration | 0.92 mg/ml (Please refer to the vial label for the specific concentration.) |
Dilution range | WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Form/Appearance | Liquid |
Conjugation | Unconjugated |
MW | 41 |
Target | atypical chemokine receptor 3 |
UniProt ID | P25106 |
Storage | Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
Buffer/Preservatives | 0.025% ProClin 300. 1XPBS pH 7, 20% Glycerol |
Alternative names | atypical chemokine receptor 3 , CMKOR1 , CXC-R7 , Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |