CXCR7 antibody [C1C2], Internal

SKU: orb1742769

Description

CXCR7 antibody recognizes C-X-C chemokine receptor type 7 (CXCR7), now known as atypical chemokine receptor 3 (ACKR3). This chemokine receptor (with a predicted molecular weight of 41 kDa) binds the chemokines CXCL11 and CXCL12 and other non-chemokine ligands such as adrenomedullin and MIF. ACKR3 plays important roles in cardiovascular and neuronal development and acts as a scavenger receptor to regulate both chemokine- and opioid peptide-dependent signaling.

Images & Validation

• Tested Applications: ELISA, FACS, ICC, IHC-Fr, IHC-P, IP, WB
• Dilution range: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CXCR7. The exact sequence is proprietary.
• Target: atypical chemokine receptor 3
• Molecular Weight: 41
• Purification: Purified by antigen-affinity chromatography.

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.025% ProClin 300. 1XPBS pH 7, 20% Glycerol
• Concentration: 0.92 mg/ml (Please refer to the vial label for the specific concentration.)
• Disclaimer: For research use only

Alternative Names

atypical chemokine receptor 3 , CMKOR1 , CXC-R7 , CXCR-7 , CXCR7 , GPR159 , RDC-1 , RDC1

Quick Database Links

Gene Symbol

atypical chemokine receptor 3

UniProt

P25106