Cart summary

You have no items in your shopping cart.

CPI-637

SKU: orb1225826

Description

A potent and selective, cell-active CBP/EP300 bromodomain inhibitor with CBP BRET EC50 of 0.03 uM; displays >700-fold selectivity over the BET bromodomains (BRD4 IC50=11.0 uM), also highly selective against other bromodomains; inhibits the expression of MYC with an EC50 of 0.60 uM in a cellular assay.(In Vitro):CPI-637 (Compound 28) inhibits MYC expression in AMO-1 cells (EC50 value of 0.60 μM) .

Images & Validation

Key Properties

CAS Number1884712-47-3
MW386.4497
Purity>98% (HPLC)
FormulaC22H22N6O
SMILESCN(N=C1C2=CN(C)N=C2)C3=C1C=C(C4=CC=CC(N5)=C4N[C@H](C)CC5=O)C=C3
TargetBromodomain
SolubilityDMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CPI637 | CPI 637

Similar Products

  • CPI-637 [orb1300446]

    99.89%

    1884712-47-3

    386.45

    C22H22N6O

    50 mg, 500 mg, 1 ml x 10 mM (in DMSO), 2 mg, 5 mg, 10 mg, 25 mg, 100 mg, 1 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

CPI-637 (orb1225826)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 120.00
10 mg
$ 150.00
25 mg
$ 290.00
50 mg
$ 490.00
100 mg
$ 720.00
500 mg
$ 1,490.00